SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03325

Signal sequence   MRPNRFSLRRSPTAVAAVALAAVLAAGAPAAQAAGAAAPTAAAAA

Length  45

Organism  Streptomyces griseus subsp. griseus (strain JCM 4626 / CBS 651.72 / NBRC 13350 / KCC S-0626 / ISP 5235)

UniProt ID  P80561,

Motif  1..45



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03325.cif

Structure  SPKB03325.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4171.83694

Aliphatic index  92

Isoelectric point  12.97714556

Charge (pH=7)   3.997971054

Topological polar surface area  1723.26

Aromaticity  0.022222222

Average rotatable bonds  2.755555556

Number of hydrogen bond donors  60

Number of hydrogen bond acceptors  57

X logP energy  -22.52272

Hydropathy 



Literature Information


Title  Streptomyces griseus aminopeptidase is a calcium-activated zinc metalloprotein. Purification and properties of the enzyme.

DOI  10.1111/j.1432-1033.1989.tb14952.x,

Publication Year  1989

PubMed ID  2503378,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.