SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03321

Signal sequence   MLRLSERNMKILFVAALVVGSVFFLLLPGPSAA

Length  33

Organism  Bos taurus (Bovine)

UniProt ID  P80311,

Motif  1..33



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03321.cif

Structure  SPKB03321.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3561.39124

Aliphatic index  141.8181818

Isoelectric point  11.47969967

Charge (pH=7)   1.999457766

Topological polar surface area  1267.84

Aromaticity  0.090909091

Average rotatable bonds  3.484848485

Number of hydrogen bond donors  44

Number of hydrogen bond acceptors  44

X logP energy  -6.13356

Hydropathy 



Literature Information


Title  The characterization of a cyclophilin-type peptidyl prolyl cis-trans-isomerase from the endoplasmic-reticulum lumen.

DOI  10.1042/bj3000871,

Publication Year  1994

PubMed ID  8010972,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.