SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03319

Signal sequence   MPLGLLWLGLALLGALHAQA

Length  20

Organism  Homo sapiens (Human)

UniProt ID  P80188,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  3BY0,

Predicted Structure ID  SPKB03319.cif

Structure  SPKB03319.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2058.55564

Aliphatic index  176

Isoelectric point  7.550323994

Charge (pH=7)   0.08889339

Topological polar surface area  694.99

Aromaticity  0.05

Average rotatable bonds  3.2

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  24

X logP energy  -0.8333

Hydropathy 



Literature Information


Title  Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase.

DOI  NA,

Publication Year  1993

PubMed ID  7683678,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.