SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03318

Signal sequence   MSLPSSRAARVPGPSGSLCALLALLLLLTPPGPLASA

Length  37

Organism  Homo sapiens (Human)

UniProt ID  P80162,

Motif  1..37



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03318.cif

Structure  SPKB03318.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3599.35124

Aliphatic index  129.4594595

Isoelectric point  10.52640717

Charge (pH=7)   1.936002961

Topological polar surface area  1323.59

Aromaticity  0

Average rotatable bonds  2.891891892

Number of hydrogen bond donors  46

Number of hydrogen bond acceptors  49

X logP energy  -13.43706

Hydropathy 



Literature Information


Title  Human and bovine granulocyte chemotactic protein-2: complete amino acid sequence and functional characterization as chemokines.

DOI  10.1021/bi00089a037,

Publication Year  1993

PubMed ID  8399143,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.