SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03317

Signal sequence   MSAFRFWSGLLMLLGFLCPRSSP

Length  23

Organism  Bos taurus (Bovine)

UniProt ID  P80109,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03317.cif

Structure  SPKB03317.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2617.18304

Aliphatic index  89.13043478

Isoelectric point  10.52640717

Charge (pH=7)   1.936002961

Topological polar surface area  906.45

Aromaticity  0.173913043

Average rotatable bonds  3.47826087

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  33

X logP energy  -5.02666

Hydropathy 



Literature Information


Title  Phosphatidylinositol-glycan-specific phospholipase D is an amphiphilic glycoprotein that in serum is associated with high-density lipoproteins.

DOI  10.1111/j.1432-1033.1992.tb16981.x,

Publication Year  1992

PubMed ID  1606959,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.