SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03315

Signal sequence   MHQVDPNLTRRKGRLAALAIAAMASASLVTVAVPATANA

Length  39

Organism  Mycobacterium bovis (strain BCG / Pasteur 1173P2)

UniProt ID  P80069,

Motif  1..39



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell surface

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  5ZX9,

Predicted Structure ID  SPKB03315.cif

Structure  SPKB03315.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3958.65624

Aliphatic index  107.9487179

Isoelectric point  12.22263642

Charge (pH=7)   3.089034907

Topological polar surface area  1659.66

Aromaticity  0

Average rotatable bonds  3.256410256

Number of hydrogen bond donors  58

Number of hydrogen bond acceptors  56

X logP energy  -19.45329

Hydropathy 



Literature Information


Title  Identification of a Mycobacterium bovis BCG 45/47-kilodalton antigen complex, an immunodominant target for antibody response after immunization with living bacteria.

DOI  10.1128/iai.61.2.742-750.1993,

Publication Year  1993

PubMed ID  8423100,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.