SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03314

Signal sequence   MGPWTHSLRAALLLVLLGVCTVSS

Length  24

Organism  Rattus norvegicus (Rat)

UniProt ID  P80067,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03314.cif

Structure  SPKB03314.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2525.06554

Aliphatic index  142.0833333

Isoelectric point  8.557478416

Charge (pH=7)   1.026915363

Topological polar surface area  931.35

Aromaticity  0.041666667

Average rotatable bonds  3.25

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  34

X logP energy  -7.02343

Hydropathy 



Literature Information


Title  Purification and characterization of cathepsin J from rat liver.

DOI  10.1111/j.1432-1033.1992.tb16647.x,

Publication Year  1992

PubMed ID  1740150,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.