SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03306

Signal sequence   MRKLTALFVASTLALGAANLAHA

Length  23

Organism  Escherichia coli (strain K12)

UniProt ID  P77754,

Motif  1..23



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03306.cif

Structure  SPKB03306.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2340.81244

Aliphatic index  127.826087

Isoelectric point  11.65178972

Charge (pH=7)   2.088595045

Topological polar surface area  923.9

Aromaticity  0.043478261

Average rotatable bonds  3.304347826

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  32

X logP energy  -8.29573

Hydropathy 



Literature Information


Title  A new periplasmic protein of Escherichia coli which is synthesized in spheroplasts but not in intact cells.

DOI  10.1128/jb.179.6.2073-2076.1997,

Publication Year  1997

PubMed ID  9068658,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.