SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03305

Signal sequence   MKHSVSVTCCALLVSSISLSYA

Length  22

Organism  Escherichia coli (strain K12)

UniProt ID  P77348,

Motif  1..22



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03305.cif

Structure  SPKB03305.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2299.74394

Aliphatic index  119.5454545

Isoelectric point  8.232794593

Charge (pH=7)   0.96379851

Topological polar surface area  890.96

Aromaticity  0.045454545

Average rotatable bonds  3.363636364

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  36

X logP energy  -10.2383

Hydropathy 



Literature Information


Title  MppA, a periplasmic binding protein essential for import of the bacterial cell wall peptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate.

DOI  10.1128/JB.180.5.1215-1223.1998,

Publication Year  1998

PubMed ID  9495761,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.