SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03301

Signal sequence   MKKNQFLKESDVTAESVFFMKRRQVLKALGISATALSLPHAAHA

Length  44

Organism  Escherichia coli (strain K12)

UniProt ID  P76342,

Motif  1..44



Activity Information


Pathway  Tat

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Tat/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03301.cif

Structure  SPKB03301.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4871.74014

Aliphatic index  88.86363636

Isoelectric point  10.95759344

Charge (pH=7)   4.182317419

Topological polar surface area  1979.64

Aromaticity  0.068181818

Average rotatable bonds  3.795454545

Number of hydrogen bond donors  69

Number of hydrogen bond acceptors  68

X logP energy  -18.55486

Hydropathy 



Literature Information


Title  Export pathway selectivity of Escherichia coli twin arginine translocation signal peptides.

DOI  10.1074/jbc.M610507200,

Publication Year  2007

PubMed ID  17218314,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.