SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03300

Signal sequence   MLKRYLVLSVATAAFSLPSLVNA

Length  23

Organism  Escherichia coli (strain K12)

UniProt ID  P76341,

Motif  1..23



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03300.cif

Structure  SPKB03300.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2464.99224

Aliphatic index  140

Isoelectric point  10.45492462

Charge (pH=7)   1.99683554

Topological polar surface area  926.89

Aromaticity  0.086956522

Average rotatable bonds  3.391304348

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  33

X logP energy  -6.58233

Hydropathy 



Literature Information


Title  The transthyretin-related protein family.

DOI  10.1046/j.1432-1033.2003.03408.x,

Publication Year  2003

PubMed ID  12542701,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.