SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03299

Signal sequence   MKKLLPCTALVMCAGMACAQA

Length  21

Organism  Escherichia coli (strain K12)

UniProt ID  P76045,

Motif  1..21



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03299.cif

Structure  SPKB03299.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2154.76684

Aliphatic index  93.33333333

Isoelectric point  8.520413618

Charge (pH=7)   1.811470084

Topological polar surface area  751.89

Aromaticity  0

Average rotatable bonds  3.380952381

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  32

X logP energy  -5.9213

Hydropathy 



Literature Information


Title  Biochemistry and regulation of a novel Escherichia coli K-12 porin protein, OmpG, which produces unusually large channels.

DOI  10.1128/JB.180.17.4452-4459.1998,

Publication Year  1998

PubMed ID  9721282,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.