SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03295

Signal sequence   MNNEETFYQAMRRQGVTRRSFLKYCSLAATSLGLGAGMAPKIAWA

Length  45

Organism  Escherichia coli (strain K12)

UniProt ID  P69739,

Motif  1..45



Activity Information


Pathway  Tat

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Tat/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03295.cif

Structure  SPKB03295.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4997.80384

Aliphatic index  65.33333333

Isoelectric point  10.44509793

Charge (pH=7)   3.937255688

Topological polar surface area  2059.16

Aromaticity  0.111111111

Average rotatable bonds  3.666666667

Number of hydrogen bond donors  75

Number of hydrogen bond acceptors  70

X logP energy  -21.47602

Hydropathy 



Literature Information


Title  Cloning and sequencing of a putative Escherichia coli [NiFe] hydrogenase-1 operon containing six open reading frames.

DOI  10.1128/jb.172.4.1969-1977.1990,

Publication Year  1990

PubMed ID  2180913,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.