SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03294

Signal sequence   MKIATIKTGLASLAMLPGLVMA

Length  22

Organism  Escherichia coli (strain K12)

UniProt ID  P69681,

Motif  1..22



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03294.cif

Structure  SPKB03294.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2230.85434

Aliphatic index  137.7272727

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  778.36

Aromaticity  0

Average rotatable bonds  3.409090909

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  31

X logP energy  -4.3685

Hydropathy 



Literature Information


Title  Mechanism of ammonia transport by Amt/MEP/Rh: structure of AmtB at 1.35 A.

DOI  10.1126/science.1101952,

Publication Year  2004

PubMed ID  15361618,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.