SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03292

Signal sequence   MALWIRSLPLLALLVFSGPGTSYA

Length  24

Organism  Gallus gallus (Chicken)

UniProt ID  P67970,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03292.cif

Structure  SPKB03292.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2577.12284

Aliphatic index  138.3333333

Isoelectric point  9.348807885

Charge (pH=7)   0.997130574

Topological polar surface area  893.88

Aromaticity  0.125

Average rotatable bonds  3.208333333

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  32

X logP energy  -3.84863

Hydropathy 



Literature Information


Title  Species variation in the amino acid sequence of insulin.

DOI  10.1016/0002-9343(66)90145-8,

Publication Year  1966

PubMed ID  5949593,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.