SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03291

Signal sequence   MMAAGPRTSLLLAFTLLCLPWTQVVGA

Length  27

Organism  Ovis aries (Sheep)

UniProt ID  P67930,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03291.cif

Structure  SPKB03291.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2861.51474

Aliphatic index  122.962963

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  1004.04

Aromaticity  0.074074074

Average rotatable bonds  3.222222222

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  37

X logP energy  -5.98733

Hydropathy 



Literature Information


Title  The primary structure of sheep pituitary growth hormone.

DOI  10.1016/0003-9861(73)90299-3,

Publication Year  1973

PubMed ID  4736985,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.