SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03288

Signal sequence   MTIKNKMLLGALLLVTSAAWAAPAT

Length  25

Organism  Escherichia coli (strain K12)

UniProt ID  P64534,

Motif  1..25



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03288.cif

Structure  SPKB03288.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2586.18954

Aliphatic index  129.2

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  944.77

Aromaticity  0.04

Average rotatable bonds  3.32

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  35

X logP energy  -6.2786

Hydropathy 



Literature Information


Title  RcnB is a periplasmic protein essential for maintaining intracellular Ni and Co concentrations in Escherichia coli.

DOI  10.1128/JB.05032-11,

Publication Year  2011

PubMed ID  21665978,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.