SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03286

Signal sequence   MRGPELRLVLLALVLCQAPLGPA

Length  23

Organism  Cavia porcellus (Guinea pig)

UniProt ID  P63152,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03286.cif

Structure  SPKB03286.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2431.03914

Aliphatic index  156.9565217

Isoelectric point  8.549845238

Charge (pH=7)   0.937778084

Topological polar surface area  881.34

Aromaticity  0

Average rotatable bonds  3.304347826

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  30

X logP energy  -4.12056

Hydropathy 



Literature Information


Title  Primary structure and tissue distribution of guinea pig gastrin-releasing peptide.

DOI  10.1111/j.1471-4159.1987.tb00998.x,

Publication Year  1987

PubMed ID  3668528,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.