SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03285

Signal sequence   MSSQQYQQQRRKFAAAFLALIFILAAVDTAEA

Length  32

Organism  Rattus norvegicus (Rat)

UniProt ID  P63090,

Motif  1..32



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03285.cif

Structure  SPKB03285.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3588.14184

Aliphatic index  95

Isoelectric point  9.296419389

Charge (pH=7)   0.999053836

Topological polar surface area  1486.21

Aromaticity  0.125

Average rotatable bonds  3.75

Number of hydrogen bond donors  51

Number of hydrogen bond acceptors  48

X logP energy  -13.40976

Hydropathy 



Literature Information


Title  Amino-terminal sequences of a novel heparin-binding protein from human, bovine, rat, and chick brain: high interspecies homology.

DOI  10.1007/BF00969930,

Publication Year  1990

PubMed ID  2388713,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.