SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03283

Signal sequence   MSIQHFRVALIPFFAAFCLPVFA

Length  23

Organism  Escherichia coli

UniProt ID  P62593,

Motif  1..23



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  1ZG4,

Predicted Structure ID  SPKB03283.cif

Structure  SPKB03283.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2626.21854

Aliphatic index  110.4347826

Isoelectric point  8.557478416

Charge (pH=7)   1.026915363

Topological polar surface area  839.84

Aromaticity  0.217391304

Average rotatable bonds  3.347826087

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  30

X logP energy  -0.96443

Hydropathy 



Literature Information


Title  Partial amino acid sequence of penicillinase coded by Escherichia coli plasmid R6K.

DOI  10.1073/pnas.75.8.3732,

Publication Year  1978

PubMed ID  358199,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.