SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03276

Signal sequence   MKALIVLGLVLLSVTVQG

Length  18

Organism  Homo sapiens (Human)

UniProt ID  P61626,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03276.cif

Structure  SPKB03276.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1854.36534

Aliphatic index  200

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  667.59

Aromaticity  0

Average rotatable bonds  3.5

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  24

X logP energy  -2.6561

Hydropathy 



Literature Information


Title  Comparison between human and bird lysozymes: Note concerning the previously observed deletion.

DOI  10.1016/0014-5793(72)80211-4,

Publication Year  1972

PubMed ID  11946553,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.