SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03275

Signal sequence   MKKIAITCALLSSLVASSVWA

Length  21

Organism  Escherichia coli (strain K12)

UniProt ID  P61316,

Motif  1..21



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03275.cif

Structure  SPKB03275.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2192.70334

Aliphatic index  139.5238095

Isoelectric point  9.676237541

Charge (pH=7)   1.935419516

Topological polar surface area  814.3

Aromaticity  0.047619048

Average rotatable bonds  3.428571429

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  31

X logP energy  -6.2687

Hydropathy 



Literature Information


Title  A novel periplasmic carrier protein involved in the sorting and transport of Escherichia coli lipoproteins destined for the outer membrane.

DOI  10.1002/j.1460-2075.1995.tb07342.x,

Publication Year  1995

PubMed ID  7628437,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.