SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03274

Signal sequence   MAQLLMVTVTFGCISLLYLLPGTLS

Length  25

Organism  Rattus norvegicus (Rat)

UniProt ID  P61312,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03274.cif

Structure  SPKB03274.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2685.33394

Aliphatic index  152

Isoelectric point  5.919503212

Charge (pH=7)   -0.064840831

Topological polar surface area  917.4

Aromaticity  0.08

Average rotatable bonds  3.4

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  36

X logP energy  -4.4773

Hydropathy 



Literature Information


Title  Peptidomics for Studying Limited Proteolysis.

DOI  10.1021/acs.jproteome.5b00820,

Publication Year  2015

PubMed ID  26479776,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.