SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03270

Signal sequence   MNSLLMITACLALVGTVWA

Length  19

Organism  Centruroides suffusus (Durango bark scorpion)

UniProt ID  P60266,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03270.cif

Structure  SPKB03270.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2007.49514

Aliphatic index  148.9473684

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  706.69

Aromaticity  0.052631579

Average rotatable bonds  3.315789474

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -3.8524

Hydropathy 



Literature Information


Title  Isolation and molecular cloning of beta-neurotoxins from the venom of the scorpion Centruroides suffusus suffusus.

DOI  10.1016/j.toxicon.2011.02.006,

Publication Year  2011

PubMed ID  21329715,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.