SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03269

Signal sequence   MTRFVLFISCFFLIDMIVEC

Length  20

Organism  Tityus obscurus (Amazonian scorpion) (Tityus cambridgei)

UniProt ID  P60214,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03269.cif

Structure  SPKB03269.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2428.02154

Aliphatic index  126.5

Isoelectric point  4.184341721

Charge (pH=7)   -1.123746837

Topological polar surface area  793.18

Aromaticity  0.2

Average rotatable bonds  3.9

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  30

X logP energy  -0.53553

Hydropathy 



Literature Information


Title  Scorpion toxins from Tityus cambridgei that affect Na(+)-channels.

DOI  10.1016/s0041-0101(01)00252-5,

Publication Year  2002

PubMed ID  11821128,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.