SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03263

Signal sequence   MRRNIFCLACLWIVQACLS

Length  19

Organism  Lymnaea stagnalis (Great pond snail) (Helix stagnalis)

UniProt ID  P58154,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  3WIP,

Predicted Structure ID  SPKB03263.cif

Structure  SPKB03263.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2240.78894

Aliphatic index  128.4210526

Isoelectric point  8.524871591

Charge (pH=7)   1.812053529

Topological polar surface area  833.12

Aromaticity  0.105263158

Average rotatable bonds  3.789473684

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  29

X logP energy  -4.78006

Hydropathy 



Literature Information


Title  A glia-derived acetylcholine-binding protein that modulates synaptic transmission.

DOI  10.1038/35077000,

Publication Year  2001

PubMed ID  11357121,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.