SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03262

Signal sequence   MARRSRHRLLLLLLRYLVVALGYHKAYG

Length  28

Organism  Homo sapiens (Human)

UniProt ID  P57087,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03262.cif

Structure  SPKB03262.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3340.08844

Aliphatic index  142.8571429

Isoelectric point  11.95406018

Charge (pH=7)   6.176939648

Topological polar surface area  1322.82

Aromaticity  0.107142857

Average rotatable bonds  3.964285714

Number of hydrogen bond donors  51

Number of hydrogen bond acceptors  42

X logP energy  -6.54155

Hydropathy 



Literature Information


Title  Vascular endothelial junction-associated molecule, a novel member of the immunoglobulin superfamily, is localized to intercellular boundaries of endothelial cells.

DOI  10.1074/jbc.M003189200,

Publication Year  2000

PubMed ID  10779521,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.