SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03260

Signal sequence   MRLPGRPGGPGGSGGLRVLLCLLLLGSRPGGCNA

Length  34

Organism  Bos taurus (Bovine)

UniProt ID  P56722,

Motif  1..34



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03260.cif

Structure  SPKB03260.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3302.96804

Aliphatic index  103.2352941

Isoelectric point  12.02344377

Charge (pH=7)   3.874021622

Topological polar surface area  1319.61

Aromaticity  0

Average rotatable bonds  3.088235294

Number of hydrogen bond donors  48

Number of hydrogen bond acceptors  45

X logP energy  -15.69402

Hydropathy 



Literature Information


Title  Post-translational modifications of ICA512, a receptor tyrosine phosphatase-like protein of secretory granules.

DOI  10.1046/j.1460-9568.1999.00677.x,

Publication Year  1999

PubMed ID  10457160,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.