SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03259

Signal sequence   MKFFLMCLIIFPIMGVLG

Length  18

Organism  Hottentotta judaicus (Black scorpion) (Buthotus judaicus)

UniProt ID  P56637,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03259.cif

Structure  SPKB03259.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2073.74524

Aliphatic index  146.1111111

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  575.25

Aromaticity  0.166666667

Average rotatable bonds  3.722222222

Number of hydrogen bond donors  20

Number of hydrogen bond acceptors  24

X logP energy  3.3877

Hydropathy 



Literature Information


Title  The putative bioactive surface of insect-selective scorpion excitatory neurotoxins.

DOI  10.1074/jbc.274.9.5769,

Publication Year  1999

PubMed ID  10026198,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.