SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03258

Signal sequence   MAPLHHILVLCVGFLTTATA

Length  20

Organism  Canis lupus familiaris (Dog) (Canis familiaris)

UniProt ID  P56513,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03258.cif

Structure  SPKB03258.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2108.58794

Aliphatic index  141.5

Isoelectric point  7.523974965

Charge (pH=7)   0.117827765

Topological polar surface area  725.48

Aromaticity  0.05

Average rotatable bonds  3.15

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  28

X logP energy  -3.6511

Hydropathy 



Literature Information


Title  Purification and complete sequence determination of the major plasma membrane substrate for cAMP-dependent protein kinase and protein kinase C in myocardium.

DOI  NA,

Publication Year  1991

PubMed ID  1710217,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.