SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03254

Signal sequence   MKGLAAALLVLVCTMALCSC

Length  20

Organism  Homo sapiens (Human)

UniProt ID  P55774,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03254.cif

Structure  SPKB03254.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2011.60354

Aliphatic index  146.5

Isoelectric point  8.045790785

Charge (pH=7)   0.811765118

Topological polar surface area  682.7

Aromaticity  0

Average rotatable bonds  3.3

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  29

X logP energy  -4.3393

Hydropathy 



Literature Information


Title  A dendritic-cell-derived C-C chemokine that preferentially attracts naive T cells.

DOI  10.1038/42716,

Publication Year  1997

PubMed ID  9192897,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.