SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03253

Signal sequence   MKVSVAALSCLMLVTALGSQA

Length  21

Organism  Homo sapiens (Human)

UniProt ID  P55773,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03253.cif

Structure  SPKB03253.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2093.58624

Aliphatic index  134.7619048

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  795.35

Aromaticity  0

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  31

X logP energy  -7.8541

Hydropathy 



Literature Information


Title  Molecular and functional characterization of two novel human C-C chemokines as inhibitors of two distinct classes of myeloid progenitors.

DOI  10.1084/jem.185.7.1163,

Publication Year  1997

PubMed ID  9104803,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.