SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03247

Signal sequence   MHRDAWLPRPAFSLTGLSLFFSLVPSGRS

Length  29

Organism  Rattus norvegicus (Rat)

UniProt ID  P54900,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03247.cif

Structure  SPKB03247.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3246.78024

Aliphatic index  84.13793103

Isoelectric point  12.19913522

Charge (pH=7)   2.089329941

Topological polar surface area  1240.6

Aromaticity  0.137931034

Average rotatable bonds  3.379310345

Number of hydrogen bond donors  45

Number of hydrogen bond acceptors  42

X logP energy  -10.54179

Hydropathy 



Literature Information


Title  Structure and function of the beta 2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif.

DOI  10.1016/0092-8674(95)90121-3,

Publication Year  1995

PubMed ID  8521473,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.