SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03246

Signal sequence   MQVLQLWLTTLISLVVAVQG

Length  20

Organism  Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

UniProt ID  P54837,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03246.cif

Structure  SPKB03246.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2212.71904

Aliphatic index  180

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  821.97

Aromaticity  0.05

Average rotatable bonds  3.6

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  28

X logP energy  -3.8111

Hydropathy 



Literature Information


Title  Proteins in the early golgi compartment of Saccharomyces cerevisiae immunoisolated by Sed5p.

DOI  10.1016/s0014-5793(00)01268-0,

Publication Year  2000

PubMed ID  10713261,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.