General Information
SPKB ID SPKB03245
Signal sequence MAEWLLSASWQRRAKAMTAAAGSAGRAAVPLLLCALLAPGGA
Length 42
Organism Homo sapiens (Human)
UniProt ID P54803,
Motif 1..42
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03245.cif
Physicochemical Information
Molecular weight 4210.00194
Aliphatic index 102.8571429
Isoelectric point 11.37963928
Charge (pH=7) 2.937479738
Topological polar surface area 1643.45
Aromaticity 0.047619048
Average rotatable bonds 3.166666667
Number of hydrogen bond donors 60
Number of hydrogen bond acceptors 56
X logP energy -15.65869
Hydropathy
Literature Information
Title Cloning and expression of cDNA encoding human galactocerebrosidase, the enzyme deficient in globoid cell leukodystrophy.
Publication Year 1993
PubMed ID 8281145,
Patent ID NA,