SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03243

Signal sequence   MLVLRNLLALVTLALLFTLSSA

Length  22

Organism  Dictyostelium discoideum (Social amoeba)

UniProt ID  P54660,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03243.cif

Structure  SPKB03243.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2372.97854

Aliphatic index  199.5454545

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  860.33

Aromaticity  0.045454545

Average rotatable bonds  3.545454545

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  30

X logP energy  -3.75363

Hydropathy 



Literature Information


Title  F-actin affinity chromatography of detergent-solubilized plasma membranes: purification and initial characterization of ponticulin from Dictyostelium discoideum.

DOI  10.1016/0076-6879(91)96007-e,

Publication Year  1991

PubMed ID  2034136,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.