General Information
SPKB ID SPKB03237
Signal sequence MGAGPSLLLAALLLLLSGDGAVRC
Length 24
Organism Homo sapiens (Human)
UniProt ID P53634,
Motif 1..24
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03237.cif
Physicochemical Information
Molecular weight 2311.82644
Aliphatic index 158.75
Isoelectric point 6.161167719
Charge (pH=7) -0.063547244
Topological polar surface area 863.49
Aromaticity 0
Average rotatable bonds 3.125
Number of hydrogen bond donors 31
Number of hydrogen bond acceptors 31
X logP energy -6.90963
Hydropathy 
Literature Information
Title The residual pro-part of cathepsin C fulfills the criteria required for an intramolecular chaperone in folding and stabilizing the human proenzyme.
DOI 10.1021/bi0008837,
Publication Year 2000
PubMed ID 11015218,
Patent ID NA,
