SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03235

Signal sequence   MKLVPVALMYLGSLAFLGADT

Length  21

Organism  Sus scrofa (Pig)

UniProt ID  P53366,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03235.cif

Structure  SPKB03235.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2210.71814

Aliphatic index  134.7619048

Isoelectric point  6.330585692

Charge (pH=7)   -0.002714665

Topological polar surface area  760.54

Aromaticity  0.095238095

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  29

X logP energy  -2.8605

Hydropathy 



Literature Information


Title  Identification and hypotensive activity of proadrenomedullin N-terminal 20 peptide (PAMP).

DOI  10.1016/0014-5793(94)00810-8,

Publication Year  1994

PubMed ID  8076689,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.