SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03231

Signal sequence   MSKLSVFFIFLFCSIATA

Length  18

Organism  Serratia marcescens

UniProt ID  P52699,

Motif  1..18



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  7XHW,

Predicted Structure ID  SPKB03231.cif

Structure  SPKB03231.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2025.49464

Aliphatic index  113.8888889

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  664.96

Aromaticity  0.222222222

Average rotatable bonds  3.555555556

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  26

X logP energy  -2.3395

Hydropathy 



Literature Information


Title  Molecular characterization of an enterobacterial metallo beta-lactamase found in a clinical isolate of Serratia marcescens that shows imipenem resistance.

DOI  10.1128/AAC.38.1.71,

Publication Year  1994

PubMed ID  8141584,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.