SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03227

Signal sequence   MKSLLVVAAVLAVGALAQGDDA

Length  22

Organism  Caenorhabditis elegans

UniProt ID  P52013,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03227.cif

Structure  SPKB03227.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2112.51264

Aliphatic index  150.9090909

Isoelectric point  4.109250801

Charge (pH=7)   -1.001417766

Topological polar surface area  838.36

Aromaticity  0

Average rotatable bonds  3.181818182

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  29

X logP energy  -7.141

Hydropathy 



Literature Information


Title  Structural and biological characterisation of the gut-associated cyclophilin B isoforms from Caenorhabditis elegans.

DOI  10.1016/s0022-2836(02)00712-x,

Publication Year  2002

PubMed ID  12215411,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.