SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03226

Signal sequence   MKRIYLLVVGLYLLSFSRA

Length  19

Organism  Rattus norvegicus (Rat)

UniProt ID  P51868,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03226.cif

Structure  SPKB03226.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2242.79424

Aliphatic index  158.9473684

Isoelectric point  10.65434506

Charge (pH=7)   2.995981815

Topological polar surface area  817.86

Aromaticity  0.157894737

Average rotatable bonds  3.894736842

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  28

X logP energy  -2.10286

Hydropathy 



Literature Information


Title  Calsequestrin is a component of smooth muscles: the skeletal- and cardiac-muscle isoforms are both present, although in highly variable amounts and ratios.

DOI  10.1042/bj3010465,

Publication Year  1994

PubMed ID  8042990,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.