General Information
SPKB ID SPKB03225
Signal sequence MSCPVPACCALLLVLGLCRA
Length 20
Organism Homo sapiens (Human)
UniProt ID P51688,
Motif 1..20
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 4MHX,
Predicted Structure ID SPKB03225.cif
Physicochemical Information
Molecular weight 2033.61264
Aliphatic index 141.5
Isoelectric point 7.916851857
Charge (pH=7) 0.750082124
Topological polar surface area 680.77
Aromaticity 0
Average rotatable bonds 3.05
Number of hydrogen bond donors 27
Number of hydrogen bond acceptors 28
X logP energy -4.41663
Hydropathy 
Literature Information
Title Cloning of the sulphamidase gene and identification of mutations in Sanfilippo A syndrome.
DOI 10.1038/ng1295-465,
Publication Year 1995
PubMed ID 7493035,
Patent ID NA,
