General Information
SPKB ID SPKB03224
Signal sequence MAGTVRTACLVVAMLLSLDFPGQA
Length 24
Organism Homo sapiens (Human)
UniProt ID P51654,
Motif 1..24
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03224.cif
Physicochemical Information
Molecular weight 2464.98214
Aliphatic index 117.9166667
Isoelectric point 6.161167719
Charge (pH=7) -0.063547244
Topological polar surface area 926.81
Aromaticity 0.041666667
Average rotatable bonds 3.25
Number of hydrogen bond donors 33
Number of hydrogen bond acceptors 34
X logP energy -8.01423
Hydropathy 
Literature Information
Title Role of Glycanation and Convertase Maturation of Soluble Glypican-3 in Inhibiting Proliferation of Hepatocellular Carcinoma Cells.
DOI 10.1021/acs.biochem.7b01208,
Publication Year 2018
PubMed ID 29345911,
Patent ID NA,
