General Information
SPKB ID SPKB03221
Signal sequence MKVSTAALAVLLCTMALWNEVFS
Length 23
Organism Rattus norvegicus (Rat)
UniProt ID P50229,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03221.cif
Physicochemical Information
Molecular weight 2499.03964
Aliphatic index 123.0434783
Isoelectric point 6.231833229
Charge (pH=7) -0.062510328
Topological polar surface area 906.64
Aromaticity 0.086956522
Average rotatable bonds 3.47826087
Number of hydrogen bond donors 33
Number of hydrogen bond acceptors 34
X logP energy -5.686
Hydropathy
Literature Information
Title Cytokine-induced neutrophil chemoattractant (CINC)-2 alpha, a novel member of rat GRO/CINCs, is a predominant chemokine produced by lipopolysaccharide-stimulated rat macrophages in culture.
Publication Year 1996
PubMed ID 8607872,
Patent ID NA,