SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03220

Signal sequence   MSLQLRSSARIPSGSISPFMRMAPLAFLLLFTLPQHLAEA

Length  40

Organism  Mus musculus (Mouse)

UniProt ID  P50228,

Motif  1..40



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03220.cif

Structure  SPKB03220.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4400.28434

Aliphatic index  110

Isoelectric point  12.19913522

Charge (pH=7)   2.090658579

Topological polar surface area  1642.53

Aromaticity  0.075

Average rotatable bonds  3.5

Number of hydrogen bond donors  57

Number of hydrogen bond acceptors  58

X logP energy  -13.00439

Hydropathy 



Literature Information


Title  Identification of mouse granulocyte chemotactic protein-2 from fibroblasts and epithelial cells. Functional comparison with natural KC and macrophage inflammatory protein-2.

DOI  NA,

Publication Year  1996

PubMed ID  8759763,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.