General Information
SPKB ID SPKB03217
Signal sequence MPVMRLFPCFLQLLAGLA
Length 18
Organism Homo sapiens (Human)
UniProt ID P49763,
Motif 1..18
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03217.cif
Physicochemical Information
Molecular weight 2020.58314
Aliphatic index 135.5555556
Isoelectric point 8.549912035
Charge (pH=7) 0.936006272
Topological polar surface area 645.43
Aromaticity 0.111111111
Average rotatable bonds 3.444444444
Number of hydrogen bond donors 22
Number of hydrogen bond acceptors 24
X logP energy -0.33983
Hydropathy
Literature Information
Title Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR.
DOI NA,
Publication Year 1994
PubMed ID 7929268,
Patent ID NA,