SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03215

Signal sequence   MMYKILCLSLLVAAVAR

Length  17

Organism  Dermatophagoides pteronyssinus (European house dust mite)

UniProt ID  P49278,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03215.cif

Structure  SPKB03215.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1895.45364

Aliphatic index  166.4705882

Isoelectric point  9.447869836

Charge (pH=7)   1.934860824

Topological polar surface area  657.3

Aromaticity  0.058823529

Average rotatable bonds  3.705882353

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  25

X logP energy  -1.47383

Hydropathy 



Literature Information


Title  Antigenic and structural analysis of group II allergens (Der f II and Der p II) from house dust mites (Dermatophagoides spp).

DOI  10.1016/0091-6749(89)90447-8,

Publication Year  1989

PubMed ID  2732406,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.