SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03213

Signal sequence   MAGSRQRGLRARVRPLFCALLLSLGRFVRG

Length  30

Organism  Homo sapiens (Human)

UniProt ID  P49257,

Motif  1..30



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  8JP4,

Predicted Structure ID  SPKB03213.cif

Structure  SPKB03213.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3358.08174

Aliphatic index  107.3333333

Isoelectric point  12.89796747

Charge (pH=7)   6.935986404

Topological polar surface area  1415.28

Aromaticity  0.066666667

Average rotatable bonds  3.766666667

Number of hydrogen bond donors  55

Number of hydrogen bond acceptors  43

X logP energy  -13.60111

Hydropathy 



Literature Information


Title  Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

DOI  10.1038/nbt810,

Publication Year  2003

PubMed ID  12665801,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.