SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03212

Signal sequence   MAAEGWIWRWGWGRRCLGRPGLPGPGPGPATPLFLLLLLGPVVA

Length  44

Organism  Canis lupus familiaris (Dog) (Canis familiaris)

UniProt ID  P49256,

Motif  1..44



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03212.cif

Structure  SPKB03212.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4693.64564

Aliphatic index  102.0454545

Isoelectric point  12.02327059

Charge (pH=7)   2.937771461

Topological polar surface area  1621.38

Aromaticity  0.113636364

Average rotatable bonds  3.045454545

Number of hydrogen bond donors  57

Number of hydrogen bond acceptors  53

X logP energy  -6.60252

Hydropathy 



Literature Information


Title  VIP36, a novel component of glycolipid rafts and exocytic carrier vesicles in epithelial cells.

DOI  10.1002/j.1460-2075.1994.tb06437.x,

Publication Year  1994

PubMed ID  8157011,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.