SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03209

Signal sequence   MRTLWIVALLLVGVEG

Length  16

Organism  Agkistrodon contortrix laticinctus (Broad-banded copperhead) (Agkistrodon mokasen laticinctus)

UniProt ID  P49121,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03209.cif

Structure  SPKB03209.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1770.20654

Aliphatic index  182.5

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  635.04

Aromaticity  0.0625

Average rotatable bonds  3.5625

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  21

X logP energy  -0.86253

Hydropathy 



Literature Information


Title  cDNA cloning and sequence analysis of a lysine-49 phospholipase A2 myotoxin from Agkistrodon contortrix laticinctus snake venom.

DOI  10.1006/abbi.1996.0042,

Publication Year  1996

PubMed ID  8579368,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.